An Insight Into Tepezza Side Effects (2024)

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Editorial Team


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Tepezza, while hailed as a groundbreaking treatment for thyroid eye disease, is also associated with a range of side effects. These side effects range from relatively minor to severe, and have been reported in varying degrees by those undergoing treatment.

Minor side effects may include muscle cramps, nausea, hair loss, or changes in taste. However, it's the severe side effects that have raised significant concerns and are at the heart of the ongoing Tepezza lawsuits. The most alarming of these side effects is the potential for permanent hearing loss and associated auditory complications.

A study reported by the Endocrine Society suggested that up to 65% of patients receiving Tepezza infusions experienced hearing-related side effects. These included subjective hearing loss, where the patient perceives a decrease in their hearing ability. Tinnitus, a persistent ringing or buzzing in the ears, was also reported by many patients. Other auditory disturbances included an ear-plugging sensation and autophony, where the patient's own voice sounds unusually loud to them.

These hearing-related side effects can be indicative of underlying damage to the inner ear labyrinth. This damage can lead to conditions such as sensorineural hearing loss, where the hair cells in the inner ear, responsible for transmitting sound to the brain, are damaged. Another potential consequence is patulous Eustachian tube, a condition where the Eustachian tube, which links the middle ear to the back of the nose and throat, stays open. This can result in symptoms like autophony.

What's particularly concerning is that these side effects aren't always temporary. There are reports of patients who have experienced ongoing or permanent hearing loss, tinnitus, and related issues following Tepezza treatment.

This connection between Tepezza and permanent hearing loss is the central focus of the ongoing lawsuits against Horizon Therapeutics, the manufacturer of Tepezza. As these legal actions unfold, a vital question remains: Were patients and healthcare professionals adequately warned about these potential risks before starting treatment with Tepezza? This question is at the heart of the current legal action, as we will discuss further in this article.

Frequently Asked Questions

  • The potential side effects of Tepezza include muscle cramps, nausea, hair loss, changes in taste, and most notably, hearing loss. Hearing-related side effects can include subjective hearing loss, tinnitus (ringing in the ears), an ear-plugging sensation, and autophony (the perception that one's own voice is unusually loud).

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